fickiandiffusiondrugrelease

由 N Abbasnezhad 著作 · 2021 · 被引用 50 次 — ... Fickian mechanism is pres- ented while the n = 0.5 the drug release mechanism can be controlled by Fickian diffusion. Whereas 0.5 < n < 1.

由 M Sanopoulou 著作 · 2018 · 被引用 19 次 — (2) In the Fickian case, the release kinetics is governed by the diffusion coefficient D. Higuchi kinetics (Eq. (1.15)) is equivalent to Fickian. Figure 1.3 ...

由 IS Bayer 著作 · 2023 · 被引用 13 次 — Higuchi model: The model defines drug release from insoluble matrices as a function of the square root of time, related to the Fickian diffusion equation. The ...

由 JM Unagolla 著作 · 2018 · 被引用 304 次 — Also, Fickian diffusion dominates the drug transport mechanism of all air-dried samples during the study period. However, the Fickian ...

In the Fickian model (Case I), n = 0.5 and the drug release are governed by diffusion. The solvent transport rate or diffusion is much greater than the process ...

2021年9月11日 — When drug release is exclusively governed by diffusion (Fickian release), then n will have a value of 0.5 for flat geometries (as in Higuchi ...

由 A Gokhale 著作 · 2014 · 被引用 62 次 — The diffusion-based drug release can be either Fickian or non-Fickian. In Fickian diffusion, the rate of release is independent of the drug ...

由 PL Ritger 著作 · 1987 · 被引用 3997 次 — For drug release from spherical polymer particles of a wide distribution, the value of the exponent n for Fickian diffusion depends on the width of the ...